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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Management of meningiomas
George A Alexiou1, Pinelopi Gogou, Sofia Markoula
1Department of Neurosurgery, University Hospital of Ioannina, Greece. alexiougrg@yahoo.gr <alexiougrg@yahoo.gr>
Clinical Neurology and Neurosurgery
|January 9, 2010
Summary
Surgery is the primary treatment for meningiomas, aiming for complete tumor removal. Alternative treatments like radiosurgery and radiotherapy are available for specific cases or recurrence.
Area of Science:
- Neurosurgery
- Oncology
Background:
- Meningiomas are primary tumors of the brain's coverings.
- Surgical resection is the principal curative treatment.
Purpose of the Study:
- To outline surgical goals and approaches for various meningioma locations.
- To discuss adjuvant therapies for meningioma treatment.
Main Methods:
- Review of surgical strategies for specific meningioma subtypes.
- Discussion of embolization, radiosurgery, radiotherapy, and chemotherapy.
Main Results:
- Gross-total resection is achievable for certain meningiomas (parasagittal, sphenoid wing, olfactory groove).
- Subtotal resection may be preferred in specific locations (petroclival, parasellar, posterior fossa) to preserve neurological function.
- Embolization, radiosurgery, and radiotherapy serve as adjuncts or alternatives to surgery.
Conclusions:
- Surgical goals (gross-total vs. subtotal resection) should be tailored to meningioma location and involvement.
- Adjuvant therapies play a role in managing residual disease or recurrence.

