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Trends in acute non-variceal bleeding in Israel in 1996-2007: a significant decrease in the rates of bleeding peptic
Tiberiu Hershcovici1, Ziona Haklai, Ethel-Sherry Gordon
1Gastroenterology Unit, Hadassah - Hebrew University Medical Centre, Jerusalem, Israel. tiberiuh@hadassah.org.il
Summary
Hospital admissions for acute non-variceal upper GI bleeding (AUGIB) significantly declined in Israel. This decrease was primarily driven by fewer cases of bleeding peptic ulcers, indicating a positive public health trend.
Area of Science:
- Gastroenterology
- Epidemiology
- Public Health
Background:
- Decreasing trends in acute non-variceal upper GI bleeding (AUGIB) admissions observed in low Helicobacter pylori (HP) prevalence regions.
- Intermediate HP prevalence in Israel necessitates local investigation of AUGIB trends.
Purpose of the Study:
- To analyze temporal trends in hospital admissions for AUGIB in Israel from 1996 to 2007.
- To identify specific causes contributing to observed AUGIB incidence changes.
Main Methods:
- Utilized the Israeli National Hospital Discharge Database (1996-2007).
- Identified AUGIB admissions using validated ICD-9-CM codes.
- Calculated age- and gender-adjusted incidence rates.
Main Results:
- Overall AUGIB admissions decreased significantly from 29.3 to 16.8 per 10(5) population/year.
- Reduced rates of duodenal and gastric ulcer bleeding were the primary drivers.
- Surgical intervention rates for bleeding control also declined significantly.
Conclusions:
- A significant decline in AUGIB incidence occurred in Israel during the study period.
- The reduction is attributed to a decrease in bleeding peptic ulcer rates.
- In-hospital mortality remained stable but increased with age.
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