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Updated: Jun 17, 2026
Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors
Published on: February 9, 2024
Pancreatoblastoma: two case reports from a medical center in Taiwan
Yi-Ling Huang1, Yung-Li Yang, Wen-Ming Hsu
1Departments of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Insights
Pancreatoblastoma (PB) is a rare pediatric pancreatic tumor. Complete surgical resection is crucial for successful treatment outcomes in children with this rare cancer.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
Background:
- Pancreatoblastoma (PB) is the most common pancreatic neoplasm in children, despite its overall rarity.
- This report details two pediatric cases of PB managed at a Taiwanese medical center.
Observation:
- Case 1: A 3.5-year-old boy with abdominal pain presented with extensive pancreatic and hepatic masses. Incomplete surgical resection followed by chemotherapy resulted in rapid progression and death.
- Case 2: A 4-year-old boy with abdominal pain underwent complete surgical resection of a pancreatic tumor, diagnosed as PB. He remains disease-free after adjuvant chemotherapy.
Findings:
- Complete tumor resection emerged as the critical differentiating factor between the two cases.
- The extent of surgical resection significantly impacts patient prognosis in pediatric pancreatoblastoma.
Implications:
- Early and complete surgical removal is paramount for improving survival rates in pediatric pancreatoblastoma.
- Further research into optimal adjuvant therapies following complete resection is warranted to enhance long-term outcomes.
Abstract:
Although pancreatoblastoma (PB) is an extremely rare tumor, it is the most common pancreatic tumor in children. We reported 2 cases of PB treated at a medical center in Taiwan. One was a 3.5-year-old boy who presented with abdominal pain. Physical examination demonstrated abdominal masses. Multiple pancreatic and hepatic masses were noted by magnetic resonance imaging. He underwent surgical resection but tumor could not be removed completely, which was confirmed by the pathology. He received chemotherapy consisting of cisplatin and doxorubicin after the surgery but the tumor progressed rapidly. He died of progressive disease and sepsis. The other case was a 4-year-old boy presented with abdominal pain. Computed tomography showed pancreatic tumor. He underwent surgical resection and pathology showed PB. He received chemotherapy after complete tumor resection. He is disease free till now. Complete tumor resection is the major difference of these 2 patients and is the most important factor affecting the outcome.