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Related Concept Videos

Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Classification and Mechanical Properties of Synthetic Polymers01:28

Classification and Mechanical Properties of Synthetic Polymers

Synthetic polymers are classified as elastomers, fibers, or plastics based on their crystallinity. Crystallinity, the degree of long-range order in the solid state, influences the mechanical properties (stretching or contracting) of elastomers. Elastomers are flexible polymers that can expand or contract easily upon the application of an external force. They have numerous crosslinks that pull them back into their original shape when stress is removed. Silicones, for instance, are highly elastic...

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Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
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Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

Recent advances in synthetic bioelastomers.

Rui Shi1, Dafu Chen1, Quanyong Liu2

  • 1Laboratory of Bone Tissue Engineering of Beijing Research Institute of Traumatology and Orthopaedics, Beijing 100035, China.

International Journal of Molecular Sciences
|January 9, 2010
PubMed
Summary
This summary is machine-generated.

This review covers biodegradable elastomers for soft tissue repair, detailing their synthesis, degradation mechanisms, and properties. It explores various polymers and their potential applications in regenerative medicine.

Keywords:
biocompatiblebiodegradablebioelastomerpoly(1, 3-trimethylene carbonate)poly(diol-citrates)poly(ester amide)spoly(ether ester)poly(polyol sebacate)spoly(ε-caprolactone)polyphosphazenespolyurethanes

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Non-chromatographic Purification of Recombinant Elastin-like Polypeptides and their Fusions with Peptides and Proteins from Escherichia coli
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Non-chromatographic Purification of Recombinant Elastin-like Polypeptides and their Fusions with Peptides and Proteins from Escherichia coli

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Non-chromatographic Purification of Recombinant Elastin-like Polypeptides and their Fusions with Peptides and Proteins from Escherichia coli

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Regenerative Medicine

Background:

  • Bioelastomers are crucial for soft tissue repair due to their mechanical properties.
  • Understanding their degradation is key to successful clinical translation.
  • Chemically synthesized bioelastomers offer tunable properties for specific applications.

Purpose of the Study:

  • To review the degradability of chemically synthesized bioelastomers for soft tissue repair.
  • To discuss in vitro and in vivo degradation mechanisms and influencing factors.
  • To present molecular designs, synthesis, properties, and applications of these materials.

Main Methods:

  • Literature review of chemically synthesized bioelastomers.
  • Analysis of degradation mechanisms (in vitro and in vivo).
  • Evaluation of structure-property relationships, mechanical performance, and biocompatibility.

Main Results:

  • Detailed overview of various biodegradable polymer classes including polyurethanes, polyphosphazenes, poly(ether/ester)s, and polyesters.
  • Discussion on factors affecting degradation rates and pathways.
  • Compilation of data on mechanical properties, biocompatibility, and potential applications.

Conclusions:

  • Chemically synthesized bioelastomers show promise for soft tissue repair.
  • Degradation behavior is influenced by molecular design and environmental factors.
  • Further research into tailored bioelastomers can advance regenerative medicine.