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Updated: Jun 17, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
[Functional magnetic resonance imaging in psychiatry and psychotherapy]
B Derntl1, U Habel, F Schneider
1Institut für Klinische, Biologische und Differentielle Psychologie, Universität Wien, Wien, Osterreich. birgit.derntl@univie.ac.at
Abstract:
technical improvements, functional magnetic resonance imaging (fMRI) has become the most popular and versatile imaging method in psychiatric research. The scope of this manuscript is to briefly introduce the basics of MR physics, the blood oxygenation level-dependent (BOLD) contrast as well as the principles of MR study design and functional data analysis. The presentation of exemplary studies on emotion recognition and empathy in schizophrenia patients will highlight the importance of MR methods in psychiatry. Finally, we will demonstrate insights into new developments that will further boost MR techniques in clinical research and will help to gain more insight into dysfunctional neural networks underlying cognitive and emotional deficits in psychiatric patients. Moreover, some techniques such as neurofeedback seem promising for evaluation of therapy effects on a behavioral and neural level.
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