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Thilo Muth1, Daniela Keller, Stephanie Michaela Puetz

  • 1Rudolf Virchow Center, DFG Research Center for Experimental Biomedicine, University of Würzburg, (Protein Mass Spectrometry and Functional Proteomics), Würzburg, Germany.

Proteomics
|January 9, 2010
PubMed

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Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...