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[Cardiovascular agents in the elderly: main rules to optimize their use]
Patrick Friocourt1, Joël Belmin
1Pôle autonomie, neurologie et prise en charge du vieillissement, centre hospitalier, Blois, France. pfriocourt@ch-blois.fr
Insights
Cardiovascular drugs are effective but underused in elders due to adverse event fears. Safe prescribing for elderly heart failure requires individualized dosing based on renal function and vital signs.
Area of Science:
- Geriatrics
- Cardiology
- Pharmacology
Background:
- Cardiovascular drugs demonstrate efficacy in treating various heart conditions.
- Adverse events associated with cardiovascular medications can be serious in older adults.
- Underutilization of key drugs like beta-blockers and ACE inhibitors in elderly heart failure patients is noted.
Purpose of the Study:
- To emphasize safe prescribing practices for cardiovascular drugs in the elderly.
- To address the underuse of essential cardiovascular medications in older populations.
- To highlight the importance of individualized dosing and risk assessment.
Main Methods:
- Review of evidence-based medicine for cardiovascular drug prescribing in geriatrics.
- Analysis of factors influencing drug efficacy and safety in elderly patients.
- Emphasis on dose adjustment based on individual patient parameters.
Main Results:
- Cardiovascular drugs, while effective, pose risks of adverse events in the elderly.
- Fear of adverse events contributes to the underuse of beta-blockers and ACE inhibitors in heart failure.
- Safe prescribing necessitates dose adjustments considering renal function and potential side effects.
Conclusions:
- Cardiovascular drug prescribing in the elderly must adhere to evidence-based guidelines.
- Individualized dose adjustments are crucial, accounting for creatinine clearance, hydration, blood pressure, and orthostatic hypotension.
- Implementing safe practices can improve the appropriate use of cardiovascular medications in older adults.
Abstract:
Effectiveness of cardiovascular drugs in the treatment of several cardiovascular diseases is widely demonstrated. These drugs may be the source of potentially serious adverse events in the old individuals and fear of these events may partly explain why beta-blockers and angiotensin converting enzyme inhibitors are underused in elders with heart failure. Cardiovascular drugs should be prescribed using safe practices, including dose adjustment taking into account the renal function and the search for conditions like orthostatic hypotension or conduction disorders. Cardiovascular drugs prescribing must be done according to evidence-based medicine in the elderly. The doses must be adjusted individually, taking into account the objectives and target doses, as the individual parameters as creatinine clearance, hydration status, blood pressure and orthostatic hypotension.
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