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The oral health needs of children after treatment for a solid tumour or lymphoma

Alison Hutton1, Moira Bradwell, Martin English

  • 1Dental Specialties Department, Birmingham Children's Hospital, Birmingham UK. alison.hutton2@nhs.net

International Journal of Paediatric Dentistry
|January 12, 2010
PubMed

Insights

Children with neuroblastoma or who received high-dose chemotherapy with stem-cell rescue (HDCSCR) have increased caries. Chemotherapy before age 3.5 is linked to microdontia, impacting permanent teeth.

Area of Science:

  • Pediatric Oncology
  • Dental Public Health
  • Late Effects of Cancer Treatment

Background:

  • Increasing survival rates in childhood cancer highlight the importance of managing late effects.
  • Oral health is crucial for nutrition, quality of life, and overall well-being in pediatric cancer patients.
  • Dental care is integral to the comprehensive management of children undergoing cancer therapy.

Purpose of the Study:

  • To assess the oral health status of children treated for solid tumors or lymphoma.
  • To identify specific oral health needs based on tumor type and treatment modality.
  • To compare the oral health of treated children with the general pediatric population.

Main Methods:

  • A cohort of 120 pediatric patients (0-17 years) was evaluated for caries, enamel opacities, microdontia, and gingivitis.
  • Data analysis involved stratification by tumor type and treatment received.
  • Oral health outcomes were compared against the UK 2003 Child Dental Health Survey.

Main Results:

  • Patients with neuroblastoma and those receiving high-dose chemotherapy with stem-cell rescue (HDCSCR) exhibited higher rates of primary tooth caries.
  • A statistically significant association (P < 0.03) was found between chemotherapy administration before 3.5 years of age and the occurrence of microdontia.
  • Specific tumor types and treatments correlate with distinct oral health challenges.

Conclusions:

  • Oral health surveillance and care are essential for all pediatric cancer survivors, especially those with neuroblastoma or who underwent HDCSCR.
  • Children receiving chemotherapy before 3.5 years should be informed about the potential for developing microdontia in their permanent teeth.
  • Tailored dental interventions are necessary to address the unique oral health sequelae in this patient population.
Abstract

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