Related Experiment Videos
Necrotising external otitis caused by Aspergillus wentii: a case report
Mycoses
|January 12, 2010
Summary
Necrotising external otitis (NEO) is a severe infection. This case highlights Aspergillus wentii as a rare cause of NEO in immunocompromised patients, emphasizing early diagnosis.
Area of Science:
- Infectious Diseases
- Mycology
- Otolaryngology
Background:
- Necrotising external otitis (NEO) is a severe, potentially fatal infection, typically affecting elderly individuals with diabetes or compromised immune systems.
- Pseudomonas species are the most common pathogens, but opportunistic infections can occur in immunocompromised hosts.
Observation:
- This report details the first documented case of NEO caused by Aspergillus wentii, a previously unrecognized human pathogen.
- The patient's immunocompromised status likely contributed to this unusual opportunistic infection.
Findings:
- Fungal NEO, as demonstrated by this Aspergillus wentii case, is associated with a significant incidence of cranial nerve palsies.
- Delayed diagnosis and treatment of fungal NEO may lead to severe morbidity, including neurological complications.
Implications:
- Early consideration of fungal infections is crucial for immunocompromised patients presenting with NEO.
- Prompt microbiological diagnosis is essential for effective treatment and improved patient outcomes in cases of fungal NEO.
Related Concept Videos
01:27Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...