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Necrotising external otitis caused by Aspergillus wentii: a case report
Abstract:
Necrotising external otitis (NEO) is a destructive, potentially fatal, infection usually seen in elderly diabetics or the immunocompromised. The commonest causative organism is Pseudomonas but immunocompromised patients are additionally susceptible to opportunistic infections. Here we describe the first reported case of NEO caused by a previously unknown human pathogen--Aspergillus wentii. A review of the literature reveals that fungal NEO is associated with a high rate of cranial nerve palsies suggesting that infections are not being treated rapidly enough to prevent morbidity. Fungal infection should be considered early in immunocompromised patients and microbiological diagnosis should be obtained wherever possible.
Insights
Necrotising external otitis (NEO) is a severe infection. This case highlights Aspergillus wentii as a rare cause of NEO in immunocompromised patients, emphasizing early diagnosis.
Area of Science:
- Infectious Diseases
- Mycology
- Otolaryngology
Background:
- Necrotising external otitis (NEO) is a severe, potentially fatal infection, typically affecting elderly individuals with diabetes or compromised immune systems.
- Pseudomonas species are the most common pathogens, but opportunistic infections can occur in immunocompromised hosts.
Observation:
- This report details the first documented case of NEO caused by Aspergillus wentii, a previously unrecognized human pathogen.
- The patient's immunocompromised status likely contributed to this unusual opportunistic infection.
Findings:
- Fungal NEO, as demonstrated by this Aspergillus wentii case, is associated with a significant incidence of cranial nerve palsies.
- Delayed diagnosis and treatment of fungal NEO may lead to severe morbidity, including neurological complications.
Implications:
- Early consideration of fungal infections is crucial for immunocompromised patients presenting with NEO.
- Prompt microbiological diagnosis is essential for effective treatment and improved patient outcomes in cases of fungal NEO.
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