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Rap1, a mercenary among the Ras-like GTPases

E W Frische1, F J T Zwartkruis

  • 1Department of Physiological Chemistry, University Medical Center Utrecht, Centre for Biomedical Genetics and Cancer Genomics Centre, Universiteitsweg 100, 584 CG Utrecht, The Netherlands.

Developmental Biology
|January 12, 2010
PubMed
Summary

The small Ras-like GTPase Rap1 protein regulates cell shape and adhesion. Genetic studies reveal Rap1 uses different effectors across organisms to control cell polarity, matrix interactions, and cell adhesion.

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