Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Disseminated sclerosis: organic basis for mental disorders and cognitive dysfunction].

E Stenager1, L Knudsen, K Jensen

  • 1Neurologisk afd N, Odense Sygehus.

Nordisk Medicin
|January 1, 1991
PubMed
Summary

Magnetic resonance imaging (MRI) enhances understanding of cognitive issues in multiple sclerosis. While MRI shows links between lesions, corpus callosum atrophy, and cognitive deficits, it does not strongly correlate psychic symptoms with MRI-verified lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Time matters: Early-phase multiple sclerosis is accompanied by considerable impairments across multiple domains.

Multiple sclerosis (Houndmills, Basingstoke, England)·2020
Same author

Response to letter regarding Tobacco smoking.

Journal of internal medicine·2020
Same author

The association between heart diseases and suicide: a nationwide cohort study.

Journal of internal medicine·2020
Same author

Hospital ethics reflection groups: a learning and development resource for clinical practice.

BMC medical ethics·2019
Same author

Risk factors of major infections in schizophrenia. A nationwide Danish register study.

Journal of psychosomatic research·2019
Same author

Prevalence of depressive disorder among patients with fibromyalgia: Systematic review and meta-analysis.

Journal of affective disorders·2019

Area of Science:

  • Neurology
  • Neuroimaging
  • Cognitive Science

Context:

  • Multiple sclerosis (MS) is a demyelinating disease affecting the central nervous system.
  • Cognitive impairment is a significant disabling symptom in MS.
  • Magnetic resonance imaging (MRI) is crucial for diagnosing and monitoring MS.

Purpose:

  • To investigate the relationship between MRI findings and cognitive deficits in multiple sclerosis.
  • To explore the correlation between specific MRI lesions, corpus callosum atrophy, and cognitive impairments.
  • To assess the association between psychic symptoms and MRI-verified lesions in MS patients.

Summary:

  • Recent studies utilizing MRI have advanced the understanding of the organic basis of cognitive defects in multiple sclerosis.

Related Experiment Videos

  • A correlation was observed between MRI-verified single lesions, atrophy of the corpus callosum, and cognitive defects.
  • However, a convincing correlation between psychic symptoms and MRI-verified lesions was not demonstrated in these studies.

    • Impact:

    • MRI findings are valuable for understanding the neurological underpinnings of cognitive dysfunction in MS.
    • The results highlight the specific structural correlates of cognitive deficits, aiding in targeted interventions.
    • Further research is needed to elucidate the complex relationship between psychic symptoms and brain pathology in MS.