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Related Concept Videos

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Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
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Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
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Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...

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Updated: Jun 17, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration
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Published on: August 7, 2019

Dirofilariasis: a rare case report.

R Singh1, J V Shwetha, J C Samantaray

  • 1Department of Microbiology, AIIMS, Ansari Nagar, New Delhi - 110 029, India.

Indian Journal of Medical Microbiology
|January 12, 2010
PubMed
Summary
This summary is machine-generated.

Human dirofilariasis, a zoonotic infection caused by Dirofilaria repens, is rarely reported in India. This case highlights a new presentation of the infection in the lower body, expanding the known spectrum of human dirofilariasis in the region.

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Area of Science:

  • Veterinary Parasitology
  • Infectious Diseases
  • Medical Entomology

Background:

  • Human dirofilariasis is a zoonotic parasitic infection primarily caused by Dirofilaria repens.
  • The prevalence and recognition of Dirofilaria repens infections in India are limited.
  • A potential focus of human infection with Dirofilaria repens has been suggested in Kerala.

Observation:

  • This report details the first case of human dirofilariasis in Eastern India.
  • Previous documented cases in India predominantly involved ocular or facial subcutaneous infections.
  • This case represents a novel presentation of Dirofilaria repens infection in the lower extremities.

Findings:

  • The study confirms a case of human dirofilariasis in Eastern India.
  • The infection presented in the lower body, a site not previously reported in India.
  • This expands the clinical manifestations of Dirofilaria repens in the human population.

Implications:

  • This finding suggests a broader geographical distribution and varied clinical presentations of human dirofilariasis in India.
  • Increased awareness and diagnostic vigilance are necessary for this zoonotic disease in non-endemic areas.
  • Further research is warranted to understand the epidemiology and transmission dynamics of Dirofilaria repens in India.