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Updated: Jun 17, 2026
Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Comparative evaluation of autogenous calvarial bone graft and alloplastic materials for secondary reconstruction of
Nandakishor Sahoo1, Indranil Deb Roy, Ajay Premanand Desai
1Department Oral and Maxillofacial Surgery, Army Dental Centre, Army Hospital (R&R), Delhi Cantt-10, India.
Objective:
To do a comparative study and evaluate the outcome in healing of reconstructed cranial defects with an autogenous bone graft vis-à-vis alloplastic materials.
Methods:
A total of 22 patients with cranial defects were selected for this study. All the subjects were men; mean age was 27 years. Secondary reconstruction was done to obturate the defects. Of the 22 patients, 11 underwent cranioplasty with autogenous calvarial bone graft, 6 patients with a titanium mesh and 5 with a polymethylmethacrylate plate.
Results:
The follow-up period ranged from 18 to 24 months. The 11 patients who were operated on with autogenous calvarial bone grafts did not develop any postoperative infection or complications. Graft uptake was complete, and the contour of the skull was improved in all the patients. Of the 5 patients operated on for secondary reconstruction with polymethylmethacrylate plates, 3 had exposure of the implant and 1 reported with secondary infection. Of the patients where secondary reconstruction was carried out with a titanium mesh only, 1 reported with secondary infection and 2 reported with thermal sensitivity. No graft resorption was detected.
Conclusions:
In our study, we concluded that autogenous calvarial bone grafts have better mechanical, biologic, and immunologic properties. This procedure allows the surgeon to reconstruct moderately large cranial defect with ease of access within single or adjacent incision to the operating site with minimal postoperative morbidity and discomfort.
