Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction to "Functionalized α-Helical Peptide Hydrogels for Neural Tissue Engineering".

ACS biomaterials science & engineering·2025

Same author

Neuromodulation for Laryngeal Dystonia: A Systematic Review.

Journal of voice : official journal of the Voice Foundation·2025

Same author

Moving Toward Biomimetic Tissue-Engineered Scaffolds.

Nanomaterials (Basel, Switzerland)·2024

Same author

Central Mechanisms and Pathophysiology of Laryngeal Dystonia: An Up-to-Date Review.

Journal of voice : official journal of the Voice Foundation·2024

Same author

"Clicking" trimeric peptides onto hybrid T<sub>8</sub>POSS nanocages and identifying synthesis limitations.

Nanoscale·2024

Same author

Retraction notice to "Viability and proliferation of rat MSCs on adhesion protein-modified PET and PU scaffolds" [Biomaterials 33/12 (2012) 8094-8103].

Biomaterials·2024

Same journal

Simultaneous Liver-kidney Versus Liver Transplantation Categorized by Pretransplant eGFR: Impact of the 2017 OPTN Policy.

Transplantation·2026

Same journal

Preformed Anti-DQ Alpha Donor-specific Antibodies and the Risk of Antibody-mediated Rejection After Kidney Transplantation.

Transplantation·2026

Same journal

People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.

Transplantation·2026

Same journal

IL-1 Receptor Blockade Modulates Inflammation During Sequential Perfusion in Ex Vivo Porcine Kidneys.

Transplantation·2026

Same journal

Regulatory T Cells Allosensitized Under the Blockade of CD80/CD86-CD28 Costimulation Prolonged Islet Allograft Survival.

Transplantation·2026

Same journal

Desensitization With Tocilizumab and IVIg: A Prospective Controlled Cohort Study in a Predominantly Black American Population.

Transplantation·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 9, 2026

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Tissue-engineered tracheal transplantation.

Silvia Baiguera¹, Martin A Birchall, Paolo Macchiarini

¹BIOAIR (Laboratory of Biomolecular and Bioengineering Airways), University of Florence, Florenz, Italy.

Transplantation

|January 12, 2010

Summary

This summary is machine-generated.

Regenerative medicine and tissue engineering offer new therapeutic options for severe airway diseases. A recent first-in-man experience demonstrates the potential of engineered trachea grafts as sustainable biological conduits.

More Related Videos

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Related Experiment Videos

Last Updated: Jan 9, 2026

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Area of Science:

Regenerative medicine
Tissue engineering
Biomaterials science

Background:

Severe large airway diseases lack effective treatments.
Tissue engineering provides novel therapeutic strategies.
Trachea transplantation faces challenges in graft survival and function.

Observation:

The trachea is an ideal organ for tissue engineering due to its critical function.
Graft success is defined by lifelong air conduction capacity.
Engineered airway implants require specific component parts and methods.

Findings:

Review of experimental methods for producing airway implants.
Successful first-in-man clinical experience with an engineered trachea.
Demonstration of a sustainable biological conduit for air conduction.

Implications:

Regenerative medicine holds promise for untreatable disorders.
Tissue-engineered trachea grafts offer a potential solution for airway disease.
This approach could revolutionize the management of large airway pathologies.