Related Experiment Video
Updated: Jun 17, 2026
Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
Lung metastasis 21 years after initial diagnosis of osteosarcoma: a case report
Ari Halldorsson1, Steven Brooks, Sam Montgomery
1Division of Cardiothoracic Surgery, Department of Surgery, Texas Tech University, Lubbock, TX, USA.
Introduction:
To the best of our knowledge, this case report describes the longest disease-free interval between primary diagnosis and metastatic recurrence of an osteosarcoma.
Case Presentation:
A 35-year-old Caucasian American man presented with asymptomatic lung metastases 21 years after being diagnosed and treated for lower extremity osteosarcoma. He underwent curative lung resection, but 2 years thereafter developed metastatic disease in the scapula and tibia and, after resection and chemotherapy, is in remission 1 year later.
Conclusion:
This case highlights the importance of long follow-up periods and continued surveillance of osteosarcoma patients after initial curative treatment.
