Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Patient-centered Care01:13

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are themselves.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaccination in individuals with Down syndrome: immune vulnerability, safety, efficacy and opportunities.

NPJ vaccines·2026
Same author

The Detection of Down Syndrome Arthritis in Clinical Practice: A Multicenter, International Pilot and Feasibility Study of a Down Syndrome-Specific Musculoskeletal Screening Tool.

American journal of medical genetics. Part A·2025
Same author

Parental perception of facilitators and barriers to health among young children with down syndrome: a qualitative study.

Frontiers in pediatrics·2023
Same author

If my hidradenitis had a voice, this is what it would say: the perspective of a young woman with Down syndrome and hidradenitis suppurativa.

The British journal of dermatology·2023
Same author

Response to Letter to the Editor by Palffy and Ghaziuddin.

American journal of medical genetics. Part A·2023
Same author

Cardiometabolic profiles in children and adults with overweight and obesity and down syndrome.

American journal of medical genetics. Part A·2022
Same journal

Things we do for no reason: Consult physical and occupational therapy for hospitalized patients with normal functional status.

Journal of hospital medicine·2026
Same journal

Informal peer diagnostic second opinion: Hospitalist practices and perspectives.

Journal of hospital medicine·2026
Same journal

Association of intervention fidelity and outcomes in implementation of the Thrive transitional care program for Medicaid-insured individuals.

Journal of hospital medicine·2026
Same journal

Association of 1- versus 2-week faculty rotations for resident teaching services on patient outcomes, learning environment and burnout.

Journal of hospital medicine·2026
Same journal

The 5R's of large language model-assisted diagnosis: A practical framework for hospitalists.

Journal of hospital medicine·2026
Same journal

Overnight consult message volume and patterns to pediatric subspecialty fellows.

Journal of hospital medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Consultative pediatrics in the new millenium.

Kishore Vellody1, Basil J Zitelli

  • 1Paul C. Gaffney Diagnostic Referral Service, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15201, USA. kishore.vellody@chp.edu

Journal of Hospital Medicine
|January 12, 2010
PubMed
Summary
This summary is machine-generated.

The Diagnostic Referral Service (DRS) at Children's Hospital of Pittsburgh has evolved significantly since 1988, mirroring the growth in pediatric hospital medicine nationwide. This evolution includes expanded responsibilities, offering a model for modern pediatric care.

Related Experiment Videos

Last Updated: Jun 17, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

Area of Science:

  • Pediatric Hospital Medicine
  • Healthcare Management
  • Clinical Operations

Background:

  • The Diagnostic Referral Service (DRS) at Children's Hospital of Pittsburgh (CHP) was established in 1988 with 5 members.
  • Pediatric hospital medicine has experienced substantial nationwide growth since 1988.
  • The DRS has also seen significant expansion in its scope and responsibilities.

Observation:

  • The DRS has adapted to evolving healthcare landscapes and patient needs.
  • There has been a trend towards increased specialization within hospital medicine.
  • The program's responsibilities have broadened in both inpatient and outpatient settings.

Findings:

  • The DRS has grown considerably in personnel and functional capacity.
  • New and enhanced responsibilities have been integrated into the DRS.
  • The program's evolution reflects broader trends in pediatric care delivery.

Implications:

  • The DRS serves as a model for effective pediatric care in contemporary healthcare settings.
  • Understanding the DRS's evolution can inform the development of similar hospitalist programs.
  • This showcases a successful adaptation of a pediatric diagnostic service to modern medical practice.