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Updated: Jun 17, 2026

Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry
Published on: May 21, 2018
TLR2 looks at lipoproteins
Mirjam Schenk1, John T Belisle, Robert L Modlin
1Division of Dermatology, UCLA School of Medicine, Los Angeles, CA 90095, USA.
Abstract:
Toll-like receptors (TLRs) have evolved to recognize lipoproteins from diverse species of bacteria. In this issue of Immunity, Kang et al. (2009) provide insight into the mechanisms by which TLR2-TLR6 heterodimers recognize diacylated liporoteins, whereas TLR2-TLR1 heterodimers recognize triacylated lipopeptides.
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