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Updated: Jun 17, 2026

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis
Published on: March 8, 2018
Use of a microvascular clip for iris fixation of an intraocular lens: a laboratory model
Jonathan H Tzu1, Neel R Desai, Esen K Akpek
1Wilmer Eye Institute, 600 N Wolfe St, Maumenee Bldg 317, Baltimore, MD 21287-9238, USA.
Abstract:
Here we present a potential novel surgical technique consisting of fixation of a posterior-chamber intraocular lens to the iris that may be used in the treatment of aphakia or the management of intraocular lens complications when capsular support has been compromised. The technique was performed in a laboratory model using cadaveric human eyes. A commercially available neurovascular clip was used to securely fasten the intraocular lens to the iris with minimal trauma. The use of a metal clip has the advantage of avoiding potential risks of suture fixation such as suture breakage. Also, this technique is easier than suturing and may potentially serve as another tool in a cornea surgeon's armamentarium.

