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Published on: January 29, 2018
Early adolescent nutritional rickets.
1Department of Orthopaedics, CNBC, Geeta Colony, Delhi, India. rachna_anila@yahoo.co.in
Journal of Orthopaedic Surgery (Hong Kong)
|January 13, 2010
Summary
Nutritional rickets in early adolescents is often diagnosed using ulna radiographs and alkaline phosphatase levels. Treatment involves vitamin D and calcium, with biochemical resolution in about 12 weeks.
Area of Science:
- Pediatrics
- Endocrinology
- Nutritional Science
Background:
- Nutritional rickets, a condition affecting bone development, can present in early adolescents.
- Early diagnosis and effective treatment are crucial for preventing long-term skeletal complications.
Purpose of the Study:
- To evaluate early adolescents diagnosed with nutritional rickets.
- To assess their response to a specific treatment regimen.
Main Methods:
- Screened 203 adolescents (aged 10-13) with symptoms suggestive of rickets.
- Utilized clinical examinations, radiographs (wrists, knees, ankles, pelvis), and biochemical tests (serum calcium, phosphate, alkaline phosphatase).
- Treated diagnosed cases with a single intramuscular dose of vitamin D (600,000 IU), oral calcium, and supplementary vitamin D, alongside dietary and sunlight advice.
Main Results:
- Diagnosed 51 adolescents (40 females, 11 males) with nutritional rickets.
- Common symptoms included knee pain (65%) and lower-limb deformity (37%); no carpopedal spasm was reported.
- Radiographic evidence of rickets was universal, particularly at the ulna (100%), with 100% showing elevated alkaline phosphatase levels.
Conclusions:
- Lower end of ulna radiographs and serum alkaline phosphatase are effective screening and monitoring tools for nutritional rickets in adolescents.
- A high prevalence of subclinical vitamin D deficiency may exist in the adolescent population.
- Treatment led to biochemical resolution within 12 weeks and radiological resolution within 5 months.
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