Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reconstruction of the radiological component of the exposome in the CONSTANCES cohort.

The Science of the total environment·2026
Same author

Perspectives of IABERD on biodosimetry strategies for a large-scale nuclear event.

International journal of radiation biology·2025
Same author

No specific impact of ultra-high dose rates on radiation-induced chromosome rearrangements.

Scientific reports·2025
Same author

Sexual dimorphism in <sup>137</sup>Cs accumulation after chronic low dose exposure in mice.

Scientific reports·2025
Same author

Multiple approaches for dosimetric characterization of a preclinical in vivo micro scanner: complementarity of experimental and numerical dose estimation.

International journal of radiation biology·2025
Same author

Preliminary analysis of the integrated EPR signals of fingernails to validate the dosimetry method based on peak-to-peak amplitudes.

International journal of radiation biology·2025

Related Experiment Video

Updated: Jun 17, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Fingernail dosimetry: current status and perspectives.

Alex Romanyukha1, Ricardo A Reyes, Francois Trompier

  • 1Naval Dosimetry Center, Bethesda, MD 20889, USA. aromanyukha@usuhs.mil

Health Physics
|January 13, 2010
PubMed
Summary

Recent research on electron paramagnetic resonance (EPR) dosimetry in fingernails reveals that mechanical stress significantly impacts radiation dose measurements. Soaking fingernails in water effectively minimizes this stress, leading to a more accurate radiation dose assessment protocol.

More Related Videos

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
10:33

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation

Published on: September 4, 2017

Related Experiment Videos

Last Updated: Jun 17, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
10:33

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation

Published on: September 4, 2017

Area of Science:

  • Radiation dosimetry
  • Biophysics
  • Materials science

Background:

  • Limited studies on fingernail electron paramagnetic resonance (EPR) dosimetry existed before 2007.
  • Previous research showed promising results but lacked completeness regarding non-radiation signals and dose variability.

Purpose of the Study:

  • To summarize recent advancements in fingernail EPR dosimetry.
  • To investigate the nature of non-radiation signals and their impact on dose measurements.
  • To develop a reliable protocol for radiation dose assessment using human fingernails.

Main Methods:

  • Analysis of radiation-induced signals in fingernail samples.
  • Characterization of non-radiation components in EPR spectra.
  • Evaluation of the effect of mechanical stress on dose response and sensitivity.
  • Investigation of fingernail mechanical properties and deformation mitigation strategies (e.g., water soaking).

Main Results:

  • Two non-radiation EPR signals in fingernails originate from mechanical stress at the cut surface.
  • Fingernails exhibit sponge-like mechanical properties, making them susceptible to deformation.
  • Mechanical stress significantly alters dose response and radiation sensitivity.
  • Water soaking effectively eliminates mechanical deformation in fingernail samples.

Conclusions:

  • Mechanical stress is a critical factor influencing EPR dosimetry in fingernails.
  • Mitigating mechanical stress, particularly through water soaking, is essential for accurate dose measurements.
  • A prototype protocol for dose measurements in human fingernails has been formulated based on these findings.