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Updated: Jun 17, 2026

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
Published on: November 19, 2012
The use of optical coherence tomography in neurology
Cédric Lamirel1, Nancy Newman, Valéerie Biousse
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Abstract:
Optical coherence tomography (OCT) is a noninvasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. OCT allows direct visualization and measurement of the topography of the optic nerve head and retinal nerve fiber layer thickness in the peripapillary and macular regions with micron-scale resolution. These measurements are of particular interest in optic neuropathies and in numerous neurologic disorders in which there is axonal loss, such as multiple sclerosis. This article provides a detailed overview of OCT and its potential applications in neurology.
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