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Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Handwashing II: Pre-procedure and Initial Procedure Steps01:19

Handwashing II: Pre-procedure and Initial Procedure Steps

The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury.  The nails must be short and clean, without nail paint...

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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
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Antiseptic skin agents for percutaneous procedures.

Norman E Lepor1, Hooman Madyoon

  • 1Cedars-Sinai Heart Institute, Los Angeles, CA, USA.

Reviews in Cardiovascular Medicine
|January 13, 2010
PubMed
Summary

Minimizing infections from implanted devices requires effective skin preparation. Alcohol-based solutions offer broad-spectrum antimicrobial activity, making them ideal for preventing device-related infections during percutaneous procedures.

Area of Science:

  • Infectious Diseases
  • Medical Device Technology
  • Antimicrobial Agents

Background:

  • Percutaneously implanted devices (e.g., pacemakers, defibrillators, prostheses) are prone to infections, complicating treatment with device removal, antibiotics, and hospitalization.
  • Skin surface contamination is a primary source of pathogens, highlighting the importance of meticulous skin preparation during device implantation.
  • Common skin preparation agents include iodophors and chlorhexidine gluconate, available in aqueous-based or alcohol-based formulations.

Purpose of the Study:

  • To evaluate the efficacy of different skin preparation agents in preventing infections associated with percutaneously implanted medical devices.
  • To compare the antimicrobial properties and suitability of aqueous-based versus alcohol-based skin preparation solutions for invasive procedures.

Main Methods:

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  • Review of current literature on skin preparation agents used in percutaneous device implantation.
  • Analysis of the antimicrobial spectrum, efficacy, and safety profiles of iodophors and chlorhexidine gluconate.
  • Comparison of aqueous-based and alcohol-based formulations regarding their application and effectiveness in reducing skin microbial counts.

Main Results:

  • Alcohol-based solutions demonstrate rapid, sustained, and broad-spectrum antimicrobial activity.
  • Traditional aqueous-based iodophors, like povidone-iodine, are suitable for mucous membrane application.
  • Minimizing skin microbial counts is crucial for preventing hardware infections during prosthesis implantation.

Conclusions:

  • Alcohol-based skin preparation agents are highly suitable for percutaneous procedures involving prosthesis implantation due to their potent antimicrobial properties.
  • Effective skin antisepsis is a critical factor in reducing the incidence of device-associated infections.
  • The choice of skin preparation agent should consider the procedure type and anatomical site to optimize infection prevention.