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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Asthma and obesity in childhood: on the road ahead
D G Peroni1, A Pietrobelli, A L Boner
1Pediatric Department, University of Verona, Verona, Italy.
Insights
Asthma and obesity link needs objective markers for accurate diagnosis, especially in children. Relying solely on self-reported symptoms can lead to overdiagnosis, necessitating careful evaluation of lung function and inflammation.
Area of Science:
- Pediatric Pulmonology
- Obesity Medicine
- Epidemiology
Background:
- Epidemiological studies indicate a correlation between asthma and obesity.
- Current asthma diagnosis, particularly in children, often relies on self-reported symptoms, which can be unreliable.
- Obesity can mimic asthma symptoms like wheezing and dyspnea, and affect exercise tolerance and symptom perception.
Purpose of the Study:
- To emphasize the need for objective markers beyond self-reported symptoms for accurate asthma diagnosis in obese children.
- To highlight the importance of characterizing asthma phenotype using objective measures.
- To caution against overdiagnosis of asthma in obese children based solely on subjective reporting.
Main Methods:
- Review of epidemiological data linking asthma and obesity.
- Discussion of the limitations of self-reported asthma diagnosis.
- Proposal for utilizing objective markers: lung function, bronchial hyper-reactivity, atopic sensitization, and lung inflammation indices.
Main Results:
- Self-reported symptoms in obese individuals may not accurately reflect asthma.
- Obesity can lead to symptoms that overlap with asthma, complicating diagnosis.
- Objective markers are crucial for differentiating true asthma from symptom overlap in obese children.
Conclusions:
- A multidisciplinary approach is essential for understanding the complex interplay between obesity and asthma.
- Physicians should use objective measurements to confirm asthma diagnosis in obese children, avoiding overdiagnosis.
- Diet and exercise may play a role in both the diagnosis and management of asthma and obesity.
Abstract:
Epidemiological data show a link between asthma and obesity, suggesting many different mechanisms that may underlie the association. However, diagnosis of asthma is often self-reported by patients or caregivers. Definition of asthma is crucial, particularly in childhood. Obesity can be associated with symptoms commonly attributed to asthma, such as wheezing, dyspnoea and sleep apnoea. Obese subjects are less fit and may have more frequent bouts of breathlessness on exertion accompanied by an exaggerated symptom perception. Therefore, the link between the two diseases should be analysed by focusing not only on reported diagnosis of asthma but also on objective markers that can better characterize the asthma phenotype. These markers should include lung function parameters, bronchial hyper-reactivity, atopic sensitization and indices of lung inflammation. As we look back and move forward, a multidisciplinary approach is increasingly necessary to understand the complexity of obesity and asthma, keeping in mind that diet and exercise could influence both diagnosis and treatment. In the meantime, in clinical settings, physicians should be cautious about diagnosing asthma in obese children on the basis of self-reported symptoms alone and should confirm the diagnosis by using objective measurements and marker evaluations that can better identify asthma phenotype and exclude overdiagnosis.
Related Concept Videos
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Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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Asthma-III: Symptoms and Complications
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Asthma III: Clinical Manifestations
