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Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Dysrhythmias VI: Management of Dysrhythmias01:25

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Pulse rhythm01:30

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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cardiac resynchronization therapy in children.

Anjan S Batra1, Seshadri Balaji

  • 1Departments of Pediatric Cardiology, Children's Hospital of Orange County, University of California, Irvine, California.

Current Cardiology Reviews
|January 13, 2010
PubMed
Summary
This summary is machine-generated.

Cardiac Resynchronization Therapy (CRT) shows promise in pediatric heart failure patients, particularly those with specific congenital heart conditions or pacing-induced cardiomyopathy. Further evidence supports its potential role in select pediatric populations.

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Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Medicine
  • Biomedical Engineering

Background:

  • Cardiac Resynchronization Therapy (CRT) is established for adult heart failure.
  • The efficacy of CRT in pediatric heart failure (CHF) remains under investigation.
  • Emerging evidence suggests potential benefits in specific pediatric groups.

Purpose of the Study:

  • To summarize the current evidence for CRT use in pediatric CHF.
  • To identify pediatric populations that may benefit from CRT.
  • To review existing studies and case reports on pediatric CRT.

Main Methods:

  • Literature review of pediatric cardiology studies.
  • Analysis of case reports and small studies on CRT in children.
  • Summary of a multi-center registry on pediatric CRT use.

Main Results:

  • CRT may be beneficial for children with pacing-induced cardiomyopathy.
  • Congenital heart disease with systemic ventricular failure is a potential indication.
  • Idiopathic dilated cardiomyopathy in children may respond to CRT.
  • Evidence includes case reports, post-operative studies, and registry data.

Conclusions:

  • CRT is a potentially valuable therapy for select pediatric CHF patients.
  • Further research is needed to define optimal use and outcomes.
  • Specific indications include heart block, congenital heart disease, and dilated cardiomyopathy.