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Updated: Jun 17, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
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A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients

Published on: October 17, 2017

Neurocritical care for neonates.

Hannah C Glass1, Sonia L Bonifacio, Susan Peloquin

  • 1Department of Neurology, University of California, Box 0663, 521 Parnassus Avenue, C-215, San Francisco, CA 94143-0663, USA. Hannah.Glass@ucsf.edu

Neurocritical Care
|January 13, 2010
PubMed
Summary

A new Neonatal Neurocritical Care Service (NNCS) was established to manage newborns at risk for neurological injury. Initial outcomes show a 20% mortality rate, but further study is needed to confirm neurodevelopmental benefits.

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Area of Science:

  • Neonatology
  • Neuroscience
  • Critical Care Medicine

Background:

  • A Neonatal Neurocritical Care Service (NNCS) was established at UCSF to address the complex needs of neonates facing neurological injury.
  • This specialized service integrates dedicated neurological care, expert neonatal medical and nursing support, advanced neuromonitoring, and neuroimaging.

Purpose of the Study:

  • To describe the establishment, patient characteristics, and initial outcomes of the new Neonatal Neurocritical Care Service.
  • To evaluate the feasibility and preliminary impact of a dedicated neurocritical care approach in a neonatal population.

Main Methods:

  • A retrospective analysis of 155 newborns evaluated by the NNCS between July 2008 and June 2009.
  • Data collected included demographics, diagnoses, length of stay, mortality, and utilization of neurophysiology and imaging resources.

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Last Updated: Jun 17, 2026

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Published on: October 17, 2017

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
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Main Results:

  • The NNCS evaluated 155 neonates, with 51 preterm and 104 term infants. Common diagnoses included hypoxic-ischemic encephalopathy (38%) and seizures (35%).
  • Mortality was approximately 20% in both preterm and term populations. Preterm infants commonly experienced intraventricular hemorrhage and periventricular hemorrhagic infarction.

Conclusions:

  • The establishment of an NNCS provides a framework for specialized neonatal neurological care.
  • While promising, further longitudinal studies are essential to ascertain if this specialized care improves long-term neurodevelopmental outcomes in newborns, similar to adult neurocritical care.
  • The 20% mortality rate highlights the critical need for effective interventions in this vulnerable population.