Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amino-functionalized bimetallic MOF nanozyme <i>via</i> solvent-assisted ligand exchange for interference-free phenolic detection.

Analytical methods : advancing methods and applications·2026
Same author

Differential Effects of Oleoyl Serine and HU-910 on Anxiety-like and Depression-like Behaviors in Male and Female WKY Rats.

International journal of molecular sciences·2026
Same author

Nanoengineered γ MnO<sub>2</sub> Accelerates the Degradation of Antibiotic-Resistant Biofilms.

Life (Basel, Switzerland)·2026
Same author

Fluorescent Carbon Dots-Antibiotic Nanocomposite Drug for the Eradication of Multidrug-Resistant Bacteria.

ACS omega·2026
Same author

Odorant-binding protein as active ingredient for fragrance release regulated by sweat.

International journal of biological macromolecules·2026
Same author

Interaction of polypeptides with hair in different reducing environments.

International journal of biological macromolecules·2026

Related Experiment Video

Updated: Jun 17, 2026

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

Microspheres of mixed proteins.

Ulyana Angel Shimanovich1, Devorah Matas, Shulamit Michaeli

  • 1Department of Chemistry and Kanbar Laboratory for Nanomaterials, Bar-Ilan University Center for Advanced Materials and Nanotechnology, Bar-Ilan University, Ramat-Gan 52900, Israel. gedanken@mail.biu.ac.il

Chemistry (Weinheim an Der Bergstrasse, Germany)
|January 13, 2010
PubMed
Summary

Researchers synthesized mixed proteinaceous microspheres (MPMs) using sonochemistry. This novel method efficiently creates BSA-GFP and BSA-CFP-GBP-YFP microspheres from native proteins.

More Related Videos

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons
11:40

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
13:00

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Published on: April 17, 2012

Related Experiment Videos

Last Updated: Jun 17, 2026

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons
11:40

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
13:00

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Published on: April 17, 2012

Area of Science:

  • Biomaterials Science
  • Chemical Engineering
  • Sonochemistry

Background:

  • Sonochemistry offers a unique method for creating microcapsules from proteins.
  • Previous work by Suslick and co-workers established ultrasound-based synthesis of proteinaceous microcapsules.
  • This study expands on prior research by synthesizing mixed protein microspheres.

Purpose of the Study:

  • To synthesize and characterize mixed proteinaceous microspheres (MPMs) using a sonochemical approach.
  • To investigate the efficiency of converting native proteins into MPMs via sonication.
  • To explore the creation of novel protein-based microstructures.

Main Methods:

  • High-intensity ultrasound was employed to synthesize proteinaceous microspheres.
  • Mixtures of bovine serum albumin (BSA) with green fluorescent protein (GFP) and a cyan fluorescent protein-glucose binding protein-yellow fluorescent fused protein (CFP-GBP-YFP) were used.
  • Characterization of the resulting BSA-GFP and BSA-(CFP-GBP-YFP) microspheres was performed.

Main Results:

  • Successfully synthesized mixed proteinaceous microspheres (MPMs) including BSA-GFP and BSA-(CFP-GBP-YFP).
  • Demonstrated the sonochemical method's capability to produce MPMs from different native proteins.
  • Provided an initial assessment of the sonochemical process's efficiency in protein conversion.

Conclusions:

  • Sonochemistry is an effective method for synthesizing mixed proteinaceous microspheres.
  • The process shows potential for efficient conversion of native proteins into functional microstructures.
  • Further characterization and application studies of these novel MPMs are warranted.