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Updated: Jun 17, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

[Stroke and psychiatric disorders].

Massimiliano Beghi¹, Cesare Maria Cornaggia, Ester Di Giacomo

¹Dipartimento di Psichiatria, Università di Milano-Bicocca, Ospedale S. Gerardo, Monza. massibeghi@libero.it

Rivista Di Psichiatria

|January 14, 2010

Summary

Psychiatric disorders, particularly depression and anxiety, are common in stroke survivors. These conditions are linked to a patient

Area of Science:

Neurology
Psychiatry
Epidemiology

Context:

Stroke survivors often experience significant psychological distress.
Understanding the prevalence and associated factors of psychiatric disorders post-stroke is crucial for effective patient care.
Previous research has highlighted the link between neurological events and mental health outcomes.

Purpose:

To determine the prevalence of depression, anxiety, aggressiveness, and personality disorders in a stroke survivor cohort.
To identify demographic and clinical factors associated with these psychiatric disorders.
To explore the relationship between psychiatric conditions and stroke characteristics.

Summary:

Depression was diagnosed in 27% of stroke survivors, anxiety in 12%, and personality disorders in 10.2%. Aggressiveness was not reported.

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Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

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Published on: January 9, 2026

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A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

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Published on: May 22, 2019

Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

Published on: January 9, 2026

A positive psychopathology profile was associated with an increased risk of depression and anxiety.

No significant correlations were found between psychiatric disorders and stroke characteristics or severity.

Impact:

Psychiatric disorders, especially depression, are prevalent in stroke survivors.
The findings underscore the importance of assessing a patient's psychopathological profile for mental health risks post-stroke.
This study suggests that stroke characteristics do not significantly influence the occurrence of these psychiatric disorders.