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A new fluorescent chemodosimeter for Hg2+: selectivity, sensitivity, and resistance to Cys and GSH
Jianjun Du1, Jiangli Fan, Xiaojun Peng
1State Key Laboratory of Fine Chemicals, Dalian University of Technology, 158 Zhongshan Road, Dalian 116012, P.R. China.
Organic Letters
|January 14, 2010
Abstract:
On the basis of the mechanism of Hg(2+)-promoted hydrolysis, a new fluorescent chemodosimeter (Rho-Hg1) is reported for single-selective and parts per billion level-sensitive detection of Hg(2+) in natural waters. Moreover, the fluorescence response of Rho-Hg1 to Hg(2+) has little interference from sulfur compounds such as cysteine and glutathione and could be used in the Hg(2+) imaging in living cells.
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