[Dengue shock syndrome]

J Docquir1, D Tuerlinckx, E Bodart

  • 1Service de Pédiatrie, Cliniques Universitaires UCL de Mont Godinne, 5530 Yvoir.

Revue Medicale De Liege
|January 15, 2010
PubMed

Insights

Dengue fever, a significant global health issue, can present with prolonged fever. Early diagnosis and treatment are crucial, especially for severe cases, to prevent fatal outcomes.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Tropical Medicine

Background:

  • Dengue fever is a growing global health concern, often underdiagnosed in non-endemic regions.
  • Prophylactic measures for dengue fever have seen limited success worldwide.
  • The disease presents a significant challenge due to its potential for severe manifestations.

Observation:

  • A 21-month-old child presented with fever of unknown origin following travel to St. Domingue.
  • Diagnostic investigations confirmed the presence of Dengue Fever.
  • The rarity of the condition in the local region contributed to initial diagnostic uncertainty.

Findings:

  • Dengue fever, while often self-limiting, can progress to severe forms.
  • Severe dengue fever is associated with substantial mortality and morbidity.
  • Delayed diagnosis and treatment significantly increase the risk of fatal outcomes.

Implications:

  • Highlights the importance of considering dengue fever in pediatric patients with unexplained fever, especially after travel to endemic areas.
  • Underscores the need for increased awareness and improved diagnostic capabilities for dengue fever in non-endemic regions.
  • Emphasizes the critical role of prompt medical intervention in managing severe dengue fever cases to improve patient prognosis.

Related Concept Videos

Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...