Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 17, 2026

Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

Exploring vision-related acupuncture point specificity with multivoxel pattern analysis.

Linling Li1, Wei Qin, Lijun Bai

  • 1Life Science Research Center, School of Electronic Engineering, Xidian University, Xi'an 710071, China.

Magnetic Resonance Imaging
|January 15, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A scalable synthesis of N-doped Si nanoparticles for high-performance Li-ion batteries.

Chemical communications (Cambridge, England)·2016
Same author

Illuminating necrosis: From mechanistic exploration to preclinical application using fluorescence molecular imaging with indocyanine green.

Scientific reports·2016
Same author

The effect and action mechanism of resveratrol on the vascular endothelial cell by high glucose treatment.

Saudi journal of biological sciences·2016
Same author

Altered resting state functional connectivity of anterior insula in young smokers.

Brain imaging and behavior·2016
Same author

Curdlan blocks the immune suppression by myeloid-derived suppressor cells and reduces tumor burden.

Immunologic research·2016
Same author

Combined image guided monitoring the pharmacokinetics of rapamycin loaded human serum albumin nanoparticles with a split luciferase reporter.

Nanoscale·2016
Same journal

Repeatability of an MRI protocol for generating habitats based on cellularity, perfusion, and hypoxia in a murine model of glioma.

Magnetic resonance imaging·2026
Same journal

Association between CMR-derived pulmonary artery pulse wave velocity and pulmonary risk factors: the multi-ethnic study of atherosclerosis COPD study.

Magnetic resonance imaging·2026
Same journal

Systematic comparison of MPRAGE and BRAVO T1-weighted MRI pulse sequences and brain morphometry in high-risk young adults.

Magnetic resonance imaging·2026
Same journal

Foot dynamic contrast-enhanced MRI for assessing microcirculatory changes after endovascular therapy in peripheral artery disease: A prospective pilot study.

Magnetic resonance imaging·2026
Same journal

Reconstruction of MRI from undersampled k-spaces of double-contrast volume acquisitions using deep neural networks.

Magnetic resonance imaging·2026
Same journal

Radiofrequency-induced heating safety of brain MRI scans at 7 T in the presence of a shoulder implant.

Magnetic resonance imaging·2026
See all related articles

This study used multi-voxel pattern analysis (MVPA) to investigate brain responses to acupuncture. Results show distinct brain activation patterns for specific acupoints, supporting acupoint specificity in neuroimaging.

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Acupuncture Research

Background:

  • Acupoint specificity is a key but debated topic in functional magnetic resonance imaging (fMRI) studies of acupuncture.
  • Previous research, often using model-based methods, has lacked strong evidence for acupoint specificity due to analytical limitations.
  • The precise neural mechanisms underlying acupuncture's effects remain incompletely understood.

Purpose of the Study:

  • To investigate the specificity of brain activation patterns elicited by acupuncture stimulation at a specific acupoint (GB37) versus a nearby nonacupoint (NAP).
  • To determine if distinct neural responses can be identified using advanced neuroimaging analysis techniques.
  • To provide empirical evidence for or against the concept of acupoint specificity in the central nervous system.

Main Methods:

More Related Videos

Monitoring Acupuncture Effects on Human Brain by fMRI
09:55

Monitoring Acupuncture Effects on Human Brain by fMRI

Published on: April 8, 2010

Related Experiment Videos

Last Updated: Jun 17, 2026

Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

Monitoring Acupuncture Effects on Human Brain by fMRI
09:55

Monitoring Acupuncture Effects on Human Brain by fMRI

Published on: April 8, 2010

  • Application of multi-voxel pattern analysis (MVPA), a data-driven neuroimaging technique.
  • Comparison of brain activity patterns evoked by stimulating a vision-related acupoint (GB37) and a nonacupoint (NAP) in close proximity.
  • Utilizing functional magnetic resonance imaging (fMRI) to capture brain responses during stimulation.

Main Results:

  • MVPA successfully differentiated neural response patterns between GB37 and NAP stimulation with accuracy significantly above chance.
  • Key brain regions, including the occipital cortex, limbic-cerebellar areas, and somatosensory cortex, showed distinct activation patterns.
  • These findings indicate that the brain processes stimulation at specific acupoints differently from nonacupoints.

Conclusions:

  • The study provides evidence supporting acupoint specificity in brain responses.
  • MVPA is an effective analytical approach for detecting subtle differences in brain activation patterns related to acupuncture.
  • Characteristic neural response patterns in the brain cortex differ between stimulation at an acupoint (GB37) and a nearby nonacupoint (NAP).