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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...

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Related Experiment Video

Updated: Jun 17, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Sunscreen products: finding the allergen...

Martine Avenel-Audran1

  • 1Service de dermatologie, CHU Angers, 49933 Angers cedex 09. MaAvenel-Audran@chu-angers.fr

European Journal of Dermatology : EJD
|January 15, 2010
PubMed
Summary
This summary is machine-generated.

Sunscreen products, like other cosmetics, can cause allergic reactions due to potential allergens. Identifying these allergens requires understanding sunscreen composition and their effects on the skin.

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Area of Science:

  • Dermatology
  • Cosmetic Science
  • Allergology

Background:

  • Sunscreen products are widely used for skin protection.
  • Repeated application of topical products can lead to skin sensitization.
  • Allergic contact dermatitis is a potential adverse reaction to cosmetic ingredients.

Purpose of the Study:

  • To elucidate the potential allergens present in sunscreen formulations.
  • To understand the mechanisms of skin sensitization induced by sunscreens.
  • To correlate specific sunscreen ingredients with allergic reactions.

Main Methods:

  • Review of sunscreen product compositions.
  • Analysis of reported cases of sunscreen-induced allergies.
  • Dermatological examination and patch testing.

Main Results:

  • Certain chemical UV filters are common allergens.
  • Fragrances and preservatives in sunscreens can also cause reactions.
  • Clinical manifestations range from contact dermatitis to photoallergic reactions.

Conclusions:

  • Sunscreen-induced allergies are a significant concern for dermatologists and consumers.
  • Knowledge of sunscreen ingredients is crucial for identifying causative allergens.
  • Preventive strategies and patient education are essential for managing sunscreen allergies.