Papilledema in isolated single-suture craniosynostosis: prevalence and predictive factors

Joyce M G Florisson1, Marie-Lise C van Veelen, Natalja Bannink

  • 1Craniofacial Center, Departments of Plastic and Reconstructive Surgery, Erasmus Medical Center Rotterdam, The Netherlands. j.florisson@erasmusmc.nl

Insights

Papilledema occurs in nearly 10% of children with scaphocephaly (sagittal synostosis) and 5.6% with trigonocephaly (metopic synostosis). Ventricular dilatation on CT scans did not predict papilledema in these patients.

Area of Science:

  • Pediatric Ophthalmology
  • Neurosurgery
  • Medical Imaging

Background:

  • Craniosynostosis, the premature fusion of cranial sutures, can affect brain development.
  • Papilledema, or swelling of the optic disc, is a potential complication that requires careful monitoring.

Purpose of the Study:

  • To determine the prevalence of papilledema in children with single-suture craniosynostosis.
  • To evaluate if ventricular dilatation on CT scans predicts papilledema in this population.

Main Methods:

  • Retrospective study of 205 children with isolated single-suture craniosynostosis.
  • Analysis of fundus examinations and preoperative CT scans for ventricular dilatation.

Main Results:

  • Papilledema occurred in 14 of 205 patients (6.8%), with 10 cases before surgery and 4 during follow-up.
  • Prevalence was 9.7% in scaphocephaly (sagittal synostosis) and 5.6% in trigonocephaly (metopic synostosis).
  • Ventricular dilatation on CT was not found to be a predictive factor for papilledema.

Conclusions:

  • The incidence of papilledema in scaphocephaly is higher than anticipated, warranting routine preoperative screening.
  • Screening is also recommended for trigonocephaly patients, with postoperative monitoring advised if uncertainty exists.

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