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Papilledema in isolated single-suture craniosynostosis: prevalence and predictive factors
Joyce M G Florisson1, Marie-Lise C van Veelen, Natalja Bannink
1Craniofacial Center, Departments of Plastic and Reconstructive Surgery, Erasmus Medical Center Rotterdam, The Netherlands. j.florisson@erasmusmc.nl
Insights
Papilledema occurs in nearly 10% of children with scaphocephaly (sagittal synostosis) and 5.6% with trigonocephaly (metopic synostosis). Ventricular dilatation on CT scans did not predict papilledema in these patients.
Area of Science:
- Pediatric Ophthalmology
- Neurosurgery
- Medical Imaging
Background:
- Craniosynostosis, the premature fusion of cranial sutures, can affect brain development.
- Papilledema, or swelling of the optic disc, is a potential complication that requires careful monitoring.
Purpose of the Study:
- To determine the prevalence of papilledema in children with single-suture craniosynostosis.
- To evaluate if ventricular dilatation on CT scans predicts papilledema in this population.
Main Methods:
- Retrospective study of 205 children with isolated single-suture craniosynostosis.
- Analysis of fundus examinations and preoperative CT scans for ventricular dilatation.
Main Results:
- Papilledema occurred in 14 of 205 patients (6.8%), with 10 cases before surgery and 4 during follow-up.
- Prevalence was 9.7% in scaphocephaly (sagittal synostosis) and 5.6% in trigonocephaly (metopic synostosis).
- Ventricular dilatation on CT was not found to be a predictive factor for papilledema.
Conclusions:
- The incidence of papilledema in scaphocephaly is higher than anticipated, warranting routine preoperative screening.
- Screening is also recommended for trigonocephaly patients, with postoperative monitoring advised if uncertainty exists.
Abstract:
The purpose of this retrospective study was to assess the prevalence of papilledema in patients with isolated craniosynostosis. Second, we wanted to assess if the presence of ventricular dilatation on computed tomography (CT) scan is a predictive factor for the occurrence of papilledema. We included 205 consecutive children with an isolated single-suture craniosynostosis, who had at least 1 fundus examination. Preoperative CT scans of the brain were examined for the presence of ventricular dilatation.Papilledema developed in 14 of 205 patients: 10 developed papilledema before surgery and 4 during the follow-up period. Ten of the patients with papilledema had a synostosis of the sagittal suture, and 4 of the metopic suture. Prevalence of papilledema in scaphocephaly was 9.7%, and in trigonocephaly, 5.6%. Based on evaluation of all CT scans, ventricular dilatation seemed not to be a predictive factor for papilledema in children with isolated craniosynostosis.The incidence of papilledema in almost 10% of scaphocephaly patients is remarkably higher than expected. Therefore, we recommend routine preoperative screening, especially for patients with scaphocephaly, but also for patients with trigonocephaly. Postoperative screening is recommended in all patients when there is any uncertainty.
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