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Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

Atypical Pneumonia

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Updated: Jun 17, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

[Bronchial aspergillosis].

I Dobbertin¹, G Friedel, R Jaki

¹Klinik Schillerhöhe, Zentrum für Pneumologie und Thoraxchirurgie der Robert-Bosch-Krankenhaus GmbH, Stuttgart. ingriddobbertin@gmx.de

Pneumologie (Stuttgart, Germany)

|January 15, 2010

Summary

This summary is machine-generated.

Bronchopulmonary aspergillosis, though challenging to diagnose, is increasingly treatable. This study details 39 cases of bronchial aspergillosis, focusing on bronchoscopic and radiological findings for better patient outcomes.

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Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

Related Experiment Videos

Last Updated: Jun 17, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

Area of Science:

Pulmonology
Mycology
Infectious Diseases

Background:

Bronchopulmonary aspergillosis is an emerging and often difficult-to-diagnose fungal infection.
Advances in antimycotic treatments have improved therapeutic outcomes.
Bronchial aspergillosis, a less common form, warrants specific clinical attention.

Purpose of the Study:

To present a series of 39 patients diagnosed with bronchial aspergillosis.
To highlight the bronchoscopic and radiological features of various forms of bronchial aspergillosis.
To contribute to the understanding and diagnosis of this condition.

Main Methods:

Retrospective analysis of 39 patients with bronchial aspergillosis.
Classification of cases into distinct subtypes: endobronchial aspergillosis, chronic necrotizing pulmonary aspergillosis (CNPA), invasive aspergillosis, Aspergillus invasion from tumors, and allergic bronchopulmonary aspergillosis (ABPA).
Detailed review of bronchoscopic and radiological findings for each case.

Main Results:

The study includes diverse presentations of bronchial aspergillosis, such as endobronchial aspergilloma and Aspergillus invasion associated with tumors.
Allergic bronchopulmonary aspergillosis (ABPA) represented the largest subgroup with 26 cases.
Findings emphasize the importance of integrating bronchoscopic and imaging data for diagnosis.

Conclusions:

Bronchial aspergillosis presents with varied clinical manifestations.
Accurate diagnosis relies on combined bronchoscopic and radiological assessment.
Further research into optimal management strategies for different forms of bronchial aspergillosis is warranted.