Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise breathing pattern during chronic altitude exposure.

I B Mekjavic1, C Moric, S V Goldberg

  • 1School of Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.

European Journal of Applied Physiology and Occupational Physiology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reasons for acceptance or nonparticipation in iAdhere: a trial of latent TB infection treatment.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2024
Same author

In pursuit of the unicorn.

Experimental physiology·2020
Same author

PlanHab Study: Consequences of combined normobaric hypoxia and bed rest on adenosine kinetics.

Scientific reports·2018
Same author

Correction to: Electrocardiogram-based predictors for arrhythmia after spinal cord injury.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2017
Same author

Assessment of the reliability of intubation and ease of use of the Cook Staged Extubation Set-an observational study.

Anaesthesia and intensive care·2017
Same author

Increased diffusion capacity maintains arterial saturation during exercise in the Quechua Indians of Chilean Altiplano.

American journal of human biology : the official journal of the Human Biology Council·2017
Same journal

Reply to the letter by morton

European journal of applied physiology and occupational physiology·1999
Same journal

Effects of caffeine, ephedrine and their combination on time to exhaustion during high-intensity exercise.

European journal of applied physiology and occupational physiology·1999
Same journal

The effect of strength training on estimates of mitochondrial density and distribution throughout muscle fibres.

European journal of applied physiology and occupational physiology·1999
Same journal

Latency to CNS oxygen toxicity in rats as a function of PCO(2) and PO(2).

European journal of applied physiology and occupational physiology·1999
Same journal

Diurnal variations in ventilatory and cardiorespiratory responses to submaximal treadmill exercise in females.

European journal of applied physiology and occupational physiology·1999
Same journal

Comparison of cardiopulmonary responses to two types of dry-land upper-body exercise testing modes in competitive swimmers.

European journal of applied physiology and occupational physiology·1999
See all related articles

High altitude exposure significantly alters breathing patterns during maximal exercise, increasing ventilation and tidal volume. These breathing adjustments occurred rapidly within the first few days of acclimatization.

Area of Science:

  • Environmental Physiology
  • Exercise Physiology
  • Altitude Medicine

Background:

  • Understanding human physiological responses to high altitude is crucial for optimizing performance and safety.
  • Breathing pattern adjustments are key to oxygen uptake during exercise under hypoxic conditions.

Purpose of the Study:

  • To investigate the changes in breathing pattern during maximal exercise following acclimatization to simulated high altitude.
  • To analyze the components of ventilation, including tidal volume and inspiratory/expiratory times, under normoxic and hypoxic conditions.

Main Methods:

  • Four subjects underwent graded exercise tests to exhaustion at simulated altitude (4247 m).
  • Breathing patterns were assessed on day 0 (normoxia), day 2, and day 7 of hypoxia.
  • Key parameters analyzed included ventilation, tidal volume (VT), inspiratory time (TI), expiratory time (TE), and their relationships.

Related Experiment Videos

Main Results:

  • Hypoxia significantly augmented ventilation, mean inspiratory flow (VT/TI), and inspiratory duty cycle (TI/TTOT).
  • Increased ventilation was driven by a larger tidal volume (VT) and shorter inspiratory time (TI).
  • The relationship between tidal volume and inspiratory time (VT-TI) showed consistent behavior across conditions, with no significant differences between normoxia and hypoxia.

Conclusions:

  • Breathing pattern adaptations to high altitude exercise occur early during acclimatization.
  • While overall ventilation increases, the fundamental relationship between tidal volume and inspiratory time remains largely preserved.
  • Further investigation into the later stages of acclimatization may reveal more subtle changes in breathing patterns.