Echovirus-4 meningitis outbreak imported from India

Federico Gobbi1, Guido Calleri, Claudia Spezia

  • 1Centre for Tropical Diseases, S. Cuore Hospital, Negrar, Verona Province, Italy. fedgobbi@tin.it

Insights

Seven young Italian travelers developed meningitis after returning from India. Virologic studies confirmed echovirus-4 as the cause, marking the first imported echovirus outbreak in Italy and highlighting enteroviruses in traveler fevers.

Area of Science:

  • Infectious Diseases
  • Virology
  • Public Health

Background:

  • Travelers returning from endemic regions are at risk for infectious diseases.
  • Enteroviruses are a common cause of febrile illness, particularly in children.
  • Imported viral outbreaks pose a challenge to public health surveillance.

Observation:

  • Seven young Italian travelers returning from India presented with meningitis.
  • Clinical presentation was consistent with viral meningitis.
  • A cluster of cases suggested a common source of infection.

Findings:

  • Virologic studies identified echovirus-4 as the causative agent.
  • This represents the first documented imported echovirus outbreak in Italy.
  • Echovirus-4 was confirmed through molecular and serologic testing.

Implications:

  • Enteroviruses should be considered in the differential diagnosis of undiagnosed fevers in travelers.
  • Enhanced surveillance for imported viral infections is crucial.
  • Understanding travel-related infectious disease transmission is vital for prevention.

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