Related Experiment Video
Updated: Jun 17, 2026

Isolation and Flow Cytometric Assessment of Neuroimmune Interactions in a Mini-Stroke Murine Model
Published on: June 20, 2025
Background And Purpose:
We investigated whether neuroglobin, a neuronal protein that protects neurons from hypoxic-ischemic injury, is upregulated in ischemic stroke.
Methods:
Neuroglobin immunoreactivity was measured in brain tissue from control subjects and patients with ischemic stroke.
Results:
Neuroglobin was detected in several brain areas, and its expression was increased in the cortical peri-infarct region after stroke.
Conclusions:
Ischemic stroke increases expression of the neuroprotective protein neuroglobin, suggesting neuroglobin may represent a novel target for stroke therapy.
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