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Updated: Jun 17, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Pacing treatment for dilated cardiomyopathy: optimization of resynchronization pacing in pediatrics

E Anne Greene1, Charles I Berul

  • 1Division of Cardiology, Children's National Medical Center, George Washington University, Washington, District of Columbia 20011, USA. eagreene@cnmc.org

Current Opinion in Cardiology
|January 16, 2010
PubMed

Insights

Cardiac resynchronization therapy (CRT) is increasingly valuable for pediatric and congenital heart disease patients with ventricular dyssynchrony. Advances in diagnostics improve patient evaluation and treatment optimization.

Area of Science:

  • Cardiology
  • Pediatric Electrophysiology

Background:

  • Understanding of pacing in pediatric and congenital heart disease is evolving.
  • Ventricular dyssynchrony and dilated cardiomyopathy are common in this population.

Purpose of the Study:

  • Critically evaluate the utility and feasibility of cardiac resynchronization therapy (CRT).
  • Summarize recent developments in CRT for pediatric and congenital heart disease.

Main Methods:

  • Review of longer-term data for pediatric and congenital heart patients.
  • Assessment of technical improvements in CRT procedures, including lead placement.
  • Utilizing innovations in echocardiography for assessing dyssynchrony and cardiac function.

Main Results:

  • Longer-term data now available for pediatric and congenital heart populations.
  • Technical CRT aspects improved, including hybrid systems and lead placement.
  • Echocardiography innovations aid in assessing mechanical and electrical dyssynchrony.

Conclusions:

  • CRT is a valuable tool for ventricular dyssynchrony and dilated cardiomyopathy in pediatric and congenital heart disease.
  • Diagnostic advances enable better patient evaluation, treatment, and optimization.
  • Refined indications and impact of CRT in this population are expected with further data collection.
Abstract

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