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Published on: August 16, 2018
A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme
Mehtab Parveen1, Zakia Khanam, Mohammad Ali
1Department of Chemistry, Aligarh Muslim University, Aligarh-202002, UP, India. mehtab_organic@rediffmail.com
Abstract:
A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT and MS spectra). The alcoholic and aqueous extracts of the leaves of C. inerme showed significant antinociceptive activity in analgaesiometer tests.
