[Care continuity for patients with congenital hypothyroidism during transition from childhood to adulthood]

Area of Science:

• Neonatal screening programs
• Pediatric endocrinology
• Thyroid disorders

Context:

• Congenital hypothyroidism (CH) screening implemented nationwide in Japan since 1979.
• Early diagnosis and treatment within 2-3 weeks of birth.
• Transient hypothyroidism necessitates reevaluation after 3 years.

Purpose:

• To outline the established diagnosis and treatment protocols for congenital hypothyroidism in Japan.
• To emphasize the importance of timely intervention for normal growth and development.
• To highlight the need for ongoing care and reevaluation in CH patients.

Summary:

• Nationwide neonatal screening effectively detects and treats congenital hypothyroidism (CH) in Japan.
• Treatment aims for rapid normalization of serum T4 levels while preventing overtreatment.
• Patients generally exhibit normal growth, indicating efficient screening and management.

Impact:

• Efficient CH screening and treatment in Japan contribute to normal growth and development in affected children.
• Pediatric and adult thyroidologists are working to ensure seamless care continuity for CH patients.
• The program serves as a model for effective management of congenital hypothyroidism.