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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Synthesis of (+/-)-bistellettadine A
Min Yu1, Susan S Pochapsky, Barry B Snider
1Department of Chemistry MS 015, Brandeis University, Waltham, Massachusetts 02454-9110, USA.
None:
Esterification of the trienoic acid with o-xylylene dibromide gave the bis ester that underwent a templated Diels-Alder reaction to afford the macrodiolide stereospecifically in a single step. The synthesis of bistellettadine A was completed in four steps by hydrolysis and side chain elaboration.
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