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Related Experiment Video

Updated: Jun 17, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

Regeneration in crinoids.

Mariko Kondo¹, Koji Akasaka

¹Misaki Marine Biological Station, Graduate School of Science and Center for Marine Biology, The University of Tokyo, 1024 Koajiro, Misaki, Miura, Kanagawa 238-0225, Japan. konmari@mmbs.s.u-tokyo.ac.jp

Development, Growth & Differentiation

|January 19, 2010

Summary

Crinoids exhibit remarkable regeneration, with migratory cells forming a blastema and regenerating tissues. These cells are considered multipotent stem cells, offering insights into regeneration and comparative stem cell biology.

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Methods for the Study of Regeneration in Stentor

Methods for the Study of Regeneration in Stentor

Published on: June 13, 2018

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Last Updated: Jun 17, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

Methods for the Study of Regeneration in Stentor

Methods for the Study of Regeneration in Stentor

Published on: June 13, 2018

Area of Science:

Developmental Biology
Echinoderm Research
Stem Cell Biology

Background:

Regeneration is a widespread biological process involving various cell types, including stem cells.
Crinoids (feather stars and sea lilies) are echinoderms known for their extensive regenerative capabilities, particularly arm regeneration.
During crinoid regeneration, coelomocytes and amoebocytes migrate to wound sites.

Purpose of the Study:

To investigate the cellular mechanisms underlying arm regeneration in crinoids.
To identify and characterize the stem cells involved in crinoid regeneration.
To provide a basis for comparative studies of stem cells.

Main Methods:

Observation of migratory cell behavior during arm regeneration in feather stars.
Analysis of cell proliferation at the blastema, coelomic canals, and brachial nerve.
Hypothesizing the multipotent nature of migrating cells based on their differentiation into new arm structures.

Main Results:

Migratory amoebocytes form a blastema at the regenerating tip.
Migratory coelomocytes contribute to the regeneration of the coelomic system.
Cell proliferation occurs in the blastema, coelomic canals, and brachial nerve, with migrating cells differentiating into new structures.

Conclusions:

Migrating cells in crinoid regeneration are presumed to be undifferentiated multipotent stem cells.
Studying crinoid regeneration offers a comparative approach to understanding stem cells.
Further molecular analyses are needed to advance knowledge of crinoid stem cells and enable comparative studies.