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Surgical therapy of arrhythmias in single-ventricle patients undergoing Fontan or Fontan conversion
Jae Gun Kwak1, Woong-Han Kim, Jeong R Lee
1Department of Cardiothoracic Surgery, Sejong General Hospital, Sejong Heart Institute, Bucheon, Korea.
Insights
Aggressive surgical management effectively controlled arrhythmias in Fontan patients, leading to improved hemodynamics and maintained atrioventricular synchrony in most cases. This study highlights successful outcomes for arrhythmia treatment post-Fontan procedure.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Cardiac Surgery
Background:
- Arrhythmias pose significant risks to Fontan hemodynamics.
- Understanding outcomes of antiarrhythmic treatments in Fontan patients is crucial for improving long-term results.
- Retrospective review of clinical outcomes for Fontan patients with arrhythmias.
Purpose of the Study:
- To evaluate the effectiveness of antiarrhythmic treatments in patients who have undergone the Fontan procedure.
- To analyze clinical outcomes associated with surgical and medical management of arrhythmias in Fontan patients.
- To assess the impact of arrhythmia treatment on hemodynamic stability and atrioventricular synchrony.
Main Methods:
- Retrospective analysis of 182 patients who underwent Fontan procedures between 1996 and 2007.
- Focus on 39 patients who experienced arrhythmias pre- or post-Fontan operation.
- Treatment strategies included surgical interventions (Fontan conversion, Cox-maze, ablation, pacemaker implantation) and medical management.
Main Results:
- 39 patients (21.4%) presented with various arrhythmias including atrial flutter, fibrillation, junctional rhythm, and sinus node dysfunction.
- Surgical interventions for atrial flutter/fibrillation in 17 patients resulted in successful management.
- 89.2% of patients achieved and maintained atrioventricular synchrony post-treatment, with 10.8% showing persistent junctional rhythm but stable hemodynamics.
Conclusions:
- Aggressive surgical management is highly effective in controlling diverse arrhythmias in Fontan patients.
- The study demonstrates successful outcomes in maintaining hemodynamic stability and atrioventricular synchrony.
- Antiarrhythmic strategies, particularly surgical interventions, significantly benefit Fontan patient management.
Background:
Arrhythmia is detrimental to Fontan hemodynamics. Clinical outcomes among Fontan patients who underwent antiarrhythmic treatment were retrospectively reviewed.
Methods:
From January 1996 to January 2007, 182 patients underwent a Fontan procedure, including Fontan conversion. Thirty-nine of the 182 patients showed various arrhythmias pre- or post-Fontan operations, and were treated surgically including Fontan conversion (18 patients) or medically. The authors analyzed the outcomes of arrhythmia treatments retrospectively.
Results:
Thirty-nine patients (21.4%) showed various arrhythmias, such as atrial flutter, atrial fibrillation, junctional rhythm, sinus node dysfunction, or brady tachyarrhythmia pre- or post-Fontan procedure. Follow-up duration was 13.1 +/- 8.7 years (11 months to 325 months).Atrial flutter and fibrillation only developed in 17 patients who received atriopulmonary connection Fontan, and who were treated by Fontan conversion with concomitant procedures such as Cox-maze procedure (two patients), right-side maze and pacemaker implantation (five patients), right atrial isthmus ablation (four patients), right atrial isthmus cryoablation and pacemaker implantation (five patients), and only pacemaker implantation (one patient). The 21 patients who showed arrhythmia at the time of the Fontan procedure underwent the following procedures concomitantly: right atrial isthmus cryoablation with pacemaker implantation (one patient), right atrial isthmus cryoablation (one patient), or pacemaker implantation (nine patients). The remaining 10 patients, who showed junctional rhythm, sinus bradycardia, or intermittent ectopic beats, were managed medically. There were two late mortalities due to protein-losing enteropathy. As a result, 33 patients (89.2%) maintained atrioventricular synchrony, 19 in sinus rhythm and 14 supported by a DDD-type pacemaker. The remaining four patients (10.8%) showed persistent junctional rhythm with a stable hemodynamic status.
Conclusions:
The various arrhythmias in Fontan patients were well controlled by aggressive surgical management.
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