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Bisphosphonates treatment and orthodontic considerations
A A Ghoneima1, E S Allam, S L Zunt
1Department of Orthodontics, Al-Azhar University Faculty of Dental Medicine, Cairo, Egypt.
Orthodontics & Craniofacial Research
|January 19, 2010
Summary
Bisphosphonates, used for osteoporosis and cancer, may affect orthodontic treatment outcomes. Orthodontists need to understand these risks and benefits for adult patients undergoing dental care.
Area of Science:
- Dental Science
- Pharmacology
- Oncology
Background:
- Bisphosphonate use is increasing for osteoporosis and chemotherapy.
- Adult orthodontic treatment is becoming more common.
- Orthodontists require knowledge of bisphosphonate effects.
Purpose of the Study:
- To review bisphosphonate use in patients undergoing orthodontic treatment.
- To discuss potential complications of bisphosphonates.
- To evaluate the impact of bisphosphonates on orthodontic outcomes.
Main Methods:
- Literature review of bisphosphonate use.
- Analysis of bisphosphonate effects on bone metabolism.
- Examination of case studies and clinical guidelines.
Main Results:
- Bisphosphonates can affect bone remodeling, potentially impacting orthodontic tooth movement.
- Risk of medication-related osteonecrosis of the jaw (MRONJ) is a concern.
- Careful patient selection and management are crucial.
Conclusions:
- Orthodontists must be aware of bisphosphonate therapy in patients.
- Risk-benefit assessment is essential for safe orthodontic treatment.
- Further research is needed on optimizing orthodontic care for bisphosphonate users.
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