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Updated: Jun 17, 2026
An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
[Surgical treatment in advanced endometrial carcinoma.]
Qing-Shui Li1, Da-Peng Li, Xiu-Rong Wu
1Department of Gynecologic Oncology, Shandong Tumor Hospital, Jinan 250117, China.
Objective:
To study the clinical value of operation in advanced endometrial carcinoma.
Methods:
A retrospective study was carried out in 78 patients with advanced endometrial carcinoma received operation in our hospital from Jan.1, 1997 to Dec. 31, 2007. The basic operation procedures were included total hysterectomy, adnexectomy, omentectomy, appendectomy and resection of metastatic lesions located in abdomino-pelvic cavity. The criteria of satisfied operation was considered that the sizes of residual leision was smaller than or equal to 2 cm, which was used to evaluate the effect of operation. The prognostic factors were also analyzed.
Results:
Among the 78 cases, the rate of ideal cytoreductive surgery was 83% (65/78), included 23 cases of no residual leisions, 42 cases of residual leisions size smaller than or equal to 2 cm, while 13 cases of residual leisions size larger than 2 cm. The survival rate of 1-year, 3-year and 5-year were 91% (61/67), 55% (28/51) and 28% (10/36), respectively. The results by single factor analysis shown that the survival rate were correlated with prognostic factors included extent of disease, ascites, size of residual lesions, circles of chemotherapy.
Conclusion:
It is important value for advanced endometrial carcinoma to ideal cytoredutive surgery followed by combined chemotherapy, while radiotherapy no further therapeutic effects.
