Related Experiment Video
Updated: Jun 17, 2026

10:52
Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Fontan extracardiac tunnel connection: fenestration or not?
Song Fu1, Klaus Valeske, Hakan Akinturk
1Department of Childrens' Heart Center, BAYI Children's Hospital, General Hospital of Beijing Military Command, Beijing 100700, China.
Chinese Medical Journal
|January 19, 2010
Summary
Fenestrating extracardiac connections (EC) in patients with univentricular heart disease reduces early mortality and pulmonary artery pressure. Fenestration closure later improves arterial oxygen saturation and exercise tolerance.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease Surgery
- Hemodynamics
Background:
- Extracardiac connection (EC) with fenestration creates a right-to-left shunt, increasing cardiac output but causing mild oxygen desaturation.
- Fenestration closure can be performed after assessing hemodynamic stability.
- This study compares outcomes of EC with and without fenestration in univentricular heart disease.
Purpose of the Study:
- To compare the outcomes of extracardiac connection (EC) with or without fenestration in patients with univentricular heart disease.
- To evaluate the impact of fenestration on mortality, pulmonary artery pressure, and oxygen saturation.
Main Methods:
- Ninety-five patients with univentricular heart disease underwent EC using Gore-Tex conduits.
- Patients were divided into two groups: Group A (with fenestration) and Group B (without fenestration).
- Outcomes including mortality, pulmonary artery pressure, oxygen saturation, thrombosis, and neurological issues were compared. 23 patients in Group A had fenestration closure.
Main Results:
- Group B (no fenestration) had significantly higher mortality (3%) and postoperative mean pulmonary artery pressure (15.1 mmHg) compared to Group A (0% mortality, 13.2 mmHg).
- No significant differences were observed in postoperative oxygen saturation, thrombosis, neurological problems, or loss of sinus rhythm between the groups.
- Fenestration closure in Group A was performed interventionally after a mean of 20-22 months.
Conclusions:
- Fenestrating an extracardiac tunnel improves acute postoperative mortality by increasing cardiac output.
- The right-to-left shunt from fenestration does not appear to cause postoperative morbidity.
- Interventional closure of fenestration can be performed once hemodynamics stabilize to enhance arterial oxygen saturation and exercise tolerance.
Related Concept Videos
Bone Markings
Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
Hemodialysis I: Introduction
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...