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Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
Route of delivery and neonatal birth trauma
Charmaine K Moczygemba1, Pangaja Paramsothy, Susan Meikle
1Department of Gynecology and Obstetrics, Emory University, Atlanta, GA, USA. cmoczygemba@gmail.com
Insights
Cesarean delivery increases the risk of certain birth traumas, like other specified birth trauma, but decreases the odds of others, such as clavicle fractures and brachial plexus injuries.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Health
- Healthcare Quality and Safety
Background:
- Birth trauma is a significant concern in obstetrics.
- Different delivery methods may be associated with varying risks of infant injury.
- Standardized definitions are crucial for comparing birth trauma rates.
Purpose of the Study:
- To compare birth trauma rates between vaginal and cesarean deliveries.
- To analyze trauma types using International Classification of Diseases codes and Agency for Healthcare Research and Quality Patient Safety Indicators (PSI).
Main Methods:
- Utilized data from the 2004-2005 Healthcare Cost and Utilization Project Nationwide Inpatient Sample.
- Included singleton infants.
- Compared rates and odds ratios for birth trauma based on delivery mode.
Main Results:
- Overall birth trauma rates were 2.45 (PSI) and 25.85 per 1000 births.
- Cesarean delivery showed increased odds of PSI birth trauma (OR 1.71), particularly "other specified birth trauma" (OR 2.61).
- Cesarean delivery demonstrated decreased odds of overall birth trauma (OR 0.55), including clavicle fractures (OR 0.07), brachial plexus injuries (OR 0.10), and scalp injuries (OR 0.55).
Conclusions:
- Infants born via cesarean delivery face distinct birth trauma risks compared to those born vaginally.
- The type of birth trauma differs significantly based on delivery method.
- Healthcare providers should be aware of these differential risks.
Objective:
We sought to examine rates of birth trauma in 2 groupings (all International Classification of Diseases, Ninth Revision codes for birth trauma, and as defined by the Agency for Healthcare Research and Quality Patient Safety Indicator [PSI]) among infants born by vaginal and cesarean delivery.
Study Design:
Data on singleton infants were obtained from the 2004-2005 Healthcare Cost and Utilization Project Nationwide Inpatient Sample.
Results:
The rates of Agency for Healthcare Research and Quality PSI and all birth trauma were 2.45 and 25.85 per 1000 births, respectively. Compared with vaginal, cesarean delivery was associated with increased odds of PSI birth trauma (odds ratio [OR], 1.71), primarily due to an increased risk for "other specified birth trauma" (OR, 2.61). Conversely, cesarean delivery was associated with decreased odds of all birth trauma (OR, 0.55), due to decreased odds of clavicle fractures (OR, 0.07), brachial plexus (OR, 0.10), and scalp injuries (OR, 0.55).
Conclusion:
Infants delivered by cesarean are at risk for different types of birth trauma from infants delivered vaginally.
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