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Updated: Jun 17, 2026
Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging
Published on: June 30, 2018
Linear and nonlinear relationships between visual stimuli, EEG and BOLD fMRI signals
Zhongming Liu1, Cristina Rios, Nanyin Zhang
1Department of Biomedical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN 55455, USA.
None:
In the present study, the cascaded interactions between stimuli and neural and hemodynamic responses were modeled using linear systems. These models provided the theoretical hypotheses that were tested against the electroencephalography (EEG) and blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) data recorded from human subjects during prolonged periods of repeated visual stimuli with a variable setting of the inter-stimulus interval (ISI) and visual contrast. Our results suggest that (1) neural response is nonlinear only when ISI<0.2 s, (2) BOLD response is nonlinear with an exclusively vascular origin when 0.25
