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Related Concept Videos

Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
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[The other pigmented lesions].

J-P Caujolle1, P Gastaud

  • 1Service d'ophtalmologie, CHU Saint Roch, 06000 Nice cedex 1, France. ncaujolle@aol.com

Journal Francais D'Ophtalmologie
|January 19, 2010
PubMed
Summary
This summary is machine-generated.

This article discusses intraocular pigmented lesions beyond melanomas and nevi. It details tumor-related and hemorrhage-related conditions and their treatments.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Pathology

Context:

  • Intraocular pigmented lesions can mimic melanoma or nevi.
  • Accurate diagnosis is crucial for appropriate management.

Purpose:

  • To review key intraocular pigmented lesions distinct from melanomas and nevi.
  • To outline diagnostic considerations and treatment options for these lesions.

Summary:

  • Discusses tumor-related pigmented lesions: melanocytomas, RPE hypertrophy/hyperplasia, combined hamartomas, and vascular pseudotumors.
  • Covers hemorrhage-related lesions: pseudotumoral AMD, exudative/hemorrhagic chorioretinopathy, choroidal hematoma, and macroaneurysm rupture.

Impact:

  • Aids clinicians in differentiating non-melanoma/nevi pigmented lesions.
  • Improves diagnostic accuracy and treatment planning for rare ocular conditions.