Related Experiment Video
Updated: Jun 17, 2026

Profiling Thiol Redox Proteome Using Isotope Tagging Mass Spectrometry
Published on: March 24, 2012
Sensing sulfur conditions: simple to complex protein regulatory mechanisms in plant thiol metabolism
Hankuil Yi1, Ashley Galant, Geoffrey E Ravilious
1Department of Biology, Washington University, St Louis, MO 63130, USA.
Abstract:
Sulfur is essential for plant growth and development, and the molecular systems for maintaining sulfur and thiol metabolism are tightly controlled. From a biochemical perspective, the regulation of plant thiol metabolism highlights nature's ability to engineer pathways that respond to multiple inputs and cellular demands under a range of conditions. In this review, we focus on the regulatory mechanisms that form the molecular basis of biochemical sulfur sensing in plants by translating the intracellular concentration of sulfur-containing compounds into control of key metabolic steps. These mechanisms range from the simple (substrate availability, thermodynamic properties of reactions, feedback inhibition, and organelle localization) to the elaborate (formation of multienzyme complexes and thiol-based redox switches). Ultimately, the dynamic interplay of these regulatory systems is critical for sensing and maintaining sulfur assimilation and thiol metabolism in plants.
Related Concept Videos
Sulfur Assimilation
Cell Signaling in Plants
Key Elements for Plant Nutrition
Riboswitches
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
Preparation and Reactions of Thiols
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein.

