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Identification of Homologous Recombination Events in Mouse Embryonic Stem Cells Using Southern Blotting and Polymerase Chain Reaction
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Anatomy of mouse recombination hot spots

Zhen K Wu1, Irina V Getun, Philippe R J Bois

  • 1Genome Plasticity Laboratory, Department of Cancer Biology, The Scripps Research Institute, Scripps Florida, Jupiter, FL 33458, USA.

Nucleic Acids Research
|January 19, 2010
PubMed
Summary

Researchers identified and characterized seven new meiotic recombination hot spots in mice, revealing diverse sequence attributes and distinct crossover profiles. This study enhances our understanding of mammalian genome recombination and hot spot regulation.

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